{"id":308,"date":"2020-04-09T16:52:56","date_gmt":"2020-04-09T14:52:56","guid":{"rendered":"http:\/\/tnroetk.cluster028.hosting.ovh.net\/?p=308"},"modified":"2025-10-30T19:34:55","modified_gmt":"2025-10-30T18:34:55","slug":"mathieu-coureuil","status":"publish","type":"post","link":"https:\/\/www.host-pathogen-biology.fr\/index.php\/2020\/04\/09\/mathieu-coureuil\/","title":{"rendered":"Mathieu Coureuil"},"content":{"rendered":"\n<div class=\"wp-block-group\"><div class=\"wp-block-group__inner-container is-layout-constrained wp-block-group-is-layout-constrained\">\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-9d6595d7 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:51.66%\">\n<figure class=\"wp-block-image size-full is-style-default\"><img loading=\"lazy\" decoding=\"async\" width=\"128\" height=\"128\" src=\"http:\/\/www.host-pathogen-biology.fr\/wp-content\/uploads\/2020\/04\/Photo-MC-2023.jpg\" alt=\"\" class=\"wp-image-1095\"\/><\/figure>\n\n\n\n<p>mathieu.coureuil@inserm.fr<br><a href=\"https:\/\/orcid.org\/0000-0001-7655-9685\">https:\/\/orcid.org\/0000-0001-7655-9685<\/a><br><a href=\"https:\/\/www.researchgate.net\/profile\/Mathieu_Coureuil\" target=\"_blank\" rel=\"noreferrer noopener\">ResearchGate<\/a><\/p>\n<\/div>\n<\/div>\n<\/div><\/div>\n\n\n\n<p>Mathieu Coureuil is team leader. <br>Mathieu Coureuil is Director of Research (DR2) at Inserm. He received his Ph.D. in Cell Biology from University Paris-Sud, France, in 2006. Since then, he studies the interaction between&nbsp;<em>N. meningitidis<\/em>&nbsp;and human endothelial cells. He demonstrated the role of the meningococcus induced endothelial cell signaling during invasion of human vessels. &nbsp;His current discovery-driven research focuses on determining the molecular mechanisms involved in the endothelial cell colonization.&nbsp;<\/p>\n\n\n\n<p>Currently, Mathieu Coureuil is interested in invasive meningococcal infections, from portal of entry to sepsis, as well as gonococcal invasiveness.<\/p>\n\n\n\n<hr class=\"wp-block-separator has-css-opacity\"\/>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-9d6595d7 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:66.66%\">\n<p class=\"has-very-dark-gray-color has-text-color has-medium-font-size\"><strong>Last News of the Lab<\/strong><br><div class=\"pt-cv-wrapper\"><div class=\"pt-cv-view pt-cv-grid pt-cv-colsys\" id=\"pt-cv-view-05995a8w6q\"><div data-id=\"pt-cv-page-1\" class=\"pt-cv-page\" data-cvc=\"1\"><div class=\"col-md-12 col-sm-12 col-xs-12 pt-cv-content-item pt-cv-2-col\" ><div class='pt-cv-ifield'><a href=\"https:\/\/www.host-pathogen-biology.fr\/index.php\/2026\/03\/10\/vulgarisation-scientifique-microcros\/\" class=\"_self pt-cv-href-thumbnail pt-cv-thumb-left\" target=\"_self\" ><img loading=\"lazy\" decoding=\"async\" width=\"150\" height=\"150\" src=\"https:\/\/www.host-pathogen-biology.fr\/wp-content\/uploads\/2026\/03\/MicroCrocs-150x150.jpg\" class=\"pt-cv-thumbnail pull-left\" alt=\"\" \/><\/a>\n<h4 class=\"pt-cv-title\"><a href=\"https:\/\/www.host-pathogen-biology.fr\/index.php\/2026\/03\/10\/vulgarisation-scientifique-microcros\/\" class=\"_self\" target=\"_self\" >Vulgarisation scientifique @MicroCros<\/a><\/h4>\n<div class=\"pt-cv-content\">10\/03\/2026 Les bact\u00e9ries manipulent nos cellules gr\u00e2ce \u00e0 la physique Audrey Laurent Granger Les bact\u00e9ries sont partout, y compris \u00e0 l\u2019int\u00e9rieur de nous. Le microbiote intestinal, bien connu, en est rempli. Mais si certaines bact\u00e9ries se retrouvent l\u00e0 o\u00f9 elles ne devraient pas et \u00e9chappent au syst\u00e8me immunitaire, elles peuvent causer des maladies\u00a0allant d\u2019une simple ...<br \/><div class=\"pt-cv-rmwrap\"><a href=\"https:\/\/www.host-pathogen-biology.fr\/index.php\/2026\/03\/10\/vulgarisation-scientifique-microcros\/\" class=\"_self pt-cv-readmore btn btn-success\" target=\"_self\">Lire La Suite\u2026<\/a><\/div><\/div><\/div><\/div>\n<div class=\"col-md-12 col-sm-12 col-xs-12 pt-cv-content-item pt-cv-2-col\" ><div class='pt-cv-ifield'><a href=\"https:\/\/www.host-pathogen-biology.fr\/index.php\/2025\/12\/20\/the-mda-promotes-bacterial-colonisation\/\" class=\"_self pt-cv-href-thumbnail pt-cv-thumb-left\" target=\"_self\" ><img loading=\"lazy\" decoding=\"async\" width=\"150\" height=\"150\" src=\"https:\/\/www.host-pathogen-biology.fr\/wp-content\/uploads\/2025\/12\/Nat-commun-150x150.jpg\" class=\"pt-cv-thumbnail pull-left\" alt=\"\" \/><\/a>\n<h4 class=\"pt-cv-title\"><a href=\"https:\/\/www.host-pathogen-biology.fr\/index.php\/2025\/12\/20\/the-mda-promotes-bacterial-colonisation\/\" class=\"_self\" target=\"_self\" >The MDA promotes bacterial colonisation by selecting hyperadhesive pili variants<\/a><\/h4>\n<div class=\"pt-cv-content\">20\/12\/2025 Neisseria meningitidis filamentous phage MDA promotes colonisation by selecting hyperadhesive pili variants Cl\u00e9mence Mouville,\u00a0Antoine Brizard,\u00a0Morgane Wuckelt,\u00a0M\u00e9lanie Montabord,\u00a0Herv\u00e9 L\u00e9cuyer,\u00a0Julie Meyer,\u00a0Anne Jamet,\u00a0B\u00e9atrice Durel,\u00a0Charlotte Izabelle,\u00a0Xavier Nassif,\u00a0Mathieu Coureuil,\u00a0Emmanuelle Bille Abstract Filamentous phages are non-lytic phages mutually beneficial to their bacterial hosts. In Neisseria meningitidis, the filamentous phage MDA is associated with invasive diseases thanks to its key role ...<br \/><div class=\"pt-cv-rmwrap\"><a href=\"https:\/\/www.host-pathogen-biology.fr\/index.php\/2025\/12\/20\/the-mda-promotes-bacterial-colonisation\/\" class=\"_self pt-cv-readmore btn btn-success\" target=\"_self\">Lire La Suite\u2026<\/a><\/div><\/div><\/div><\/div>\n<div class=\"col-md-12 col-sm-12 col-xs-12 pt-cv-content-item pt-cv-2-col\" ><div class='pt-cv-ifield'><a href=\"https:\/\/www.host-pathogen-biology.fr\/index.php\/2025\/12\/05\/meningococci-reshape-host-membranes-to-recruit-their-own-signaling-receptors\/\" class=\"_self pt-cv-href-thumbnail pt-cv-thumb-left\" target=\"_self\" ><img loading=\"lazy\" decoding=\"async\" width=\"150\" height=\"150\" src=\"https:\/\/www.host-pathogen-biology.fr\/wp-content\/uploads\/2025\/12\/Nat-commun-150x150.jpg\" class=\"pt-cv-thumbnail pull-left\" alt=\"\" \/><\/a>\n<h4 class=\"pt-cv-title\"><a href=\"https:\/\/www.host-pathogen-biology.fr\/index.php\/2025\/12\/05\/meningococci-reshape-host-membranes-to-recruit-their-own-signaling-receptors\/\" class=\"_self\" target=\"_self\" >Meningococci reshape host membranes to recruit their own signaling receptors<\/a><\/h4>\n<div class=\"pt-cv-content\">05\/12\/2025. Meningococci drive host membrane tubulation to recruit their signaling receptors Audrey Laurent-Granger, K\u00e9vin Sollier, Bruno Saubamea, Virginie Mignon, Nicolas Goudin, Ya\u00eblle Wormser, Morgane Wuckelt, Mahmoud Rifai, Thomas Heng, Lya L\u2019hermitte, Marta Conflitti, Julie Meyer, Herv\u00e9 Lecuyer, Anne Jamet, Nicolas Borghi, Philippe Girard, Emmanuelle Bille, Gr\u00e9gory Lavieu, Eric Rubinstein, Stefano Marullo &amp; Mathieu Coureuil Abstract ...<br \/><div class=\"pt-cv-rmwrap\"><a href=\"https:\/\/www.host-pathogen-biology.fr\/index.php\/2025\/12\/05\/meningococci-reshape-host-membranes-to-recruit-their-own-signaling-receptors\/\" class=\"_self pt-cv-readmore btn btn-success\" target=\"_self\">Lire La Suite\u2026<\/a><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:33.33%\">\n<p class=\"has-very-dark-gray-color has-text-color has-medium-font-size\"><strong>Team Members (<em>Neisseria meningitidis<\/em>)<br><\/strong><ul class=\"lcp_catlist\" id=\"lcp_instance_0\"><li class=\"current\"><a href=\"https:\/\/www.host-pathogen-biology.fr\/index.php\/2020\/04\/09\/mathieu-coureuil\/\">Mathieu Coureuil<\/a><\/li><li><a href=\"https:\/\/www.host-pathogen-biology.fr\/index.php\/2020\/04\/09\/emmanuelle-bille\/\">Emmanuelle Bille<\/a><\/li><li><a href=\"https:\/\/www.host-pathogen-biology.fr\/index.php\/2020\/04\/07\/xavier-nassif\/\">Xavier Nassif<\/a><\/li><li><a href=\"https:\/\/www.host-pathogen-biology.fr\/index.php\/2025\/11\/03\/mariam-wehbi\/\">Mariam Wehbi<\/a><\/li><li><a href=\"https:\/\/www.host-pathogen-biology.fr\/index.php\/2023\/01\/25\/morgane-wuckelt\/\">Morgane Wuckelt<\/a><\/li><li><a href=\"https:\/\/www.host-pathogen-biology.fr\/index.php\/2025\/02\/04\/lison-reboul\/\">Lison Reboul<\/a><\/li><li><a href=\"https:\/\/www.host-pathogen-biology.fr\/index.php\/2023\/01\/26\/julie-brousseau\/\">Julie Brousseau<\/a><\/li><\/ul><\/p>\n\n\n\n<p class=\"has-very-dark-gray-color has-text-color has-medium-font-size\"><\/p>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-css-opacity\"\/>\n\n\n\n<p class=\"has-very-dark-gray-color has-text-color has-medium-font-size\"><strong>Last 25 Publications<\/strong> <\/p>\n\n\n\n<!-- load from cache<br> --><ol><li>Mouville, C, Brizard, A, Wuckelt, M, Montabord, M, L\u00e9cuyer, H, Meyer, J <i>et al.<\/i>. Neisseria meningitidis filamentous phage MDA promotes colonisation by selecting hyperadhesive pili variants. Nat Commun. 2025;17 (1):744. doi: <a href='http:\/\/dx.doi.org\/10.1038\/s41467-025-67441-w'>10.1038\/s41467-025-67441-w<\/a>. PubMed <a href='http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/41422109'>PMID:41422109<\/a> PubMed Central <a href='http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC12819557'>PMC12819557<\/a>.<\/li><li>Laurent-Granger, A, Sollier, K, Saubamea, B, Mignon, V, Goudin, N, Wormser, Y <i>et al.<\/i>. Meningococci drive host membrane tubulation to recruit their signaling receptors. Nat Commun. 2025;16 (1):10433. doi: <a href='http:\/\/dx.doi.org\/10.1038\/s41467-025-65436-1'>10.1038\/s41467-025-65436-1<\/a>. PubMed <a href='http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/41290585'>PMID:41290585<\/a> PubMed Central <a href='http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC12647851'>PMC12647851<\/a>.<\/li><li>Jamet, A, Fu, X, Dietrich, C, Bellon, N, Attailia, M, Uyar, E <i>et al.<\/i>. Immune response and clinical severity are shaped by skin-adapted <i>Staphylococcus aureus<\/i> in chronically infected patients. Sci Transl Med. 2025;17 (813):eadq7985. doi: <a href='http:\/\/dx.doi.org\/10.1126\/scitranslmed.adq7985'>10.1126\/scitranslmed.adq7985<\/a>. PubMed <a href='http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/40864680'>PMID:40864680<\/a> .<\/li><li>B\u00f6hning, J, Graham, M, Coureuil, M, Tarafder, AK, Meyer, J, Nassif, X <i>et al.<\/i>. Structure of the virulence-associated <i>Neisseria meningitidis<\/i> filamentous bacteriophage MDA&#x3a6;. Proc Natl Acad Sci U S A. 2025;122 (25):e2420157122. doi: <a href='http:\/\/dx.doi.org\/10.1073\/pnas.2420157122'>10.1073\/pnas.2420157122<\/a>. PubMed <a href='http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/40540604'>PMID:40540604<\/a> PubMed Central <a href='http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC12207478'>PMC12207478<\/a>.<\/li><li>Bille, E, Schubert-Unkmeir, A, Coureuil, M. Neisseria meningitidis. Trends Microbiol. 2025;33 (3):370-371. doi: <a href='http:\/\/dx.doi.org\/10.1016\/j.tim.2025.01.001'>10.1016\/j.tim.2025.01.001<\/a>. PubMed <a href='http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/39863510'>PMID:39863510<\/a> .<\/li><li>Wuckelt, M, Laurent, A, Mouville, C, Meyer, J, Jamet, A, Lecuyer, H <i>et al.<\/i>. Expanding the genetic toolbox for <i>Neisseria meningitidis<\/i> with efficient tools for unmarked gene editing, complementation, and labeling. Appl Environ Microbiol. 2024;90 (9):e0088024. doi: <a href='http:\/\/dx.doi.org\/10.1128\/aem.00880-24'>10.1128\/aem.00880-24<\/a>. PubMed <a href='http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/39140741'>PMID:39140741<\/a> PubMed Central <a href='http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC11409642'>PMC11409642<\/a>.<\/li><li>Ziveri, J, Le Guennec, L, Dos Santos Souza, I, Barnier, JP, Walter, SM, Diallo, Y <i>et al.<\/i>. Angiopoietin-like 4 protects against endothelial dysfunction during bacterial sepsis. Nat Microbiol. 2024;9 (9):2434-2447. doi: <a href='http:\/\/dx.doi.org\/10.1038\/s41564-024-01760-4'>10.1038\/s41564-024-01760-4<\/a>. PubMed <a href='http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/39103571'>PMID:39103571<\/a> .<\/li><li>Sereme, Y, Schrimp, C, Faury, H, Agapoff, M, Lefebvre-Wloszczowski, E, Chang Marchand, Y <i>et al.<\/i>. A live attenuated vaccine to prevent severe neonatal <i>Escherichia coli<\/i> K1 infections. Nat Commun. 2024;15 (1):3021. doi: <a href='http:\/\/dx.doi.org\/10.1038\/s41467-024-46775-x'>10.1038\/s41467-024-46775-x<\/a>. PubMed <a href='http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/38589401'>PMID:38589401<\/a> PubMed Central <a href='http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC11001983'>PMC11001983<\/a>.<\/li><li>Rytter, H, Roger, K, Chhuon, C, Ding, X, Coureuil, M, Jamet, A <i>et al.<\/i>. Dual proteomics of infected macrophages reveal bacterial and host players involved in the Francisella intracellular life cycle and cell to cell dissemination by merocytophagy. Sci Rep. 2024;14 (1):7797. doi: <a href='http:\/\/dx.doi.org\/10.1038\/s41598-024-58261-x'>10.1038\/s41598-024-58261-x<\/a>. PubMed <a href='http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/38565565'>PMID:38565565<\/a> PubMed Central <a href='http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC10987565'>PMC10987565<\/a>.<\/li><li>Ding, X, Robbe-Masselot, C, Fu, X, L\u00e9onard, R, Marsac, B, Dauriat, CJG <i>et al.<\/i>. Airway environment drives the selection of quorum sensing mutants and promote Staphylococcus aureus chronic lifestyle. Nat Commun. 2023;14 (1):8135. doi: <a href='http:\/\/dx.doi.org\/10.1038\/s41467-023-43863-2'>10.1038\/s41467-023-43863-2<\/a>. PubMed <a href='http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/38065959'>PMID:38065959<\/a> PubMed Central <a href='http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC10709412'>PMC10709412<\/a>.<\/li><li>Wu, S, Coureuil, M, Nassif, X, Tautz, L. NMA1982 is a Novel Phosphatase and Potential Virulence Factor in <i>Neisseria meningitidis<\/i>. bioRxiv. 2023; :. doi: <a href='http:\/\/dx.doi.org\/10.1101\/2023.05.23.541968'>10.1101\/2023.05.23.541968<\/a>. PubMed <a href='http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/37292688'>PMID:37292688<\/a> PubMed Central <a href='http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC10245925'>PMC10245925<\/a>.<\/li><li>Sch\u00f6nherr-Hellec, S, Chatzopoulou, E, Barnier, JP, Atlas, Y, Dupichaud, S, Guilbert, T <i>et al.<\/i>. Implantation of engineered human microvasculature to study human infectious diseases in mouse models. iScience. 2023;26 (4):106286. doi: <a href='http:\/\/dx.doi.org\/10.1016\/j.isci.2023.106286'>10.1016\/j.isci.2023.106286<\/a>. PubMed <a href='http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/36942053'>PMID:36942053<\/a> PubMed Central <a href='http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC10024136'>PMC10024136<\/a>.<\/li><li>Ding, X, Fu, X, Euphrasie, D, Ferroni, A, Sermet-Gaudelus, I, Charbit, A <i>et al.<\/i>. Genomic analysis of Staphylococcus aureus sequential isolates from lungs of patients with cystic fibrosis. Microbes Infect. 2023;25 (6):105124. doi: <a href='http:\/\/dx.doi.org\/10.1016\/j.micinf.2023.105124'>10.1016\/j.micinf.2023.105124<\/a>. PubMed <a href='http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/36871931'>PMID:36871931<\/a> .<\/li><li>Marullo, S, Scott, MGH, Enslen, H, Coureuil, M. Mechanical Activation of the &#x3b2;<sub>2<\/sub>-Adrenergic Receptor by Meningococcus: A Historical and Future Perspective Analysis of How a Bacterial Probe Can Reveal Signalling Pathways in Endothelial Cells, and a Unique Mode of Receptor Activation Involving Its N-Terminal Glycan Chains. Front Endocrinol (Lausanne). 2022;13 :883568. doi: <a href='http:\/\/dx.doi.org\/10.3389\/fendo.2022.883568'>10.3389\/fendo.2022.883568<\/a>. PubMed <a href='http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/35586623'>PMID:35586623<\/a> PubMed Central <a href='http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC9108228'>PMC9108228<\/a>.<\/li><li>Ramond, E, Lepissier, A, Ding, X, Bouvier, C, Tan, X, Euphrasie, D <i>et al.<\/i>. Lung-Adapted Staphylococcus aureus Isolates With Dysfunctional Agr System Trigger a Proinflammatory Response. J Infect Dis. 2022;226 (7):1276-1285. doi: <a href='http:\/\/dx.doi.org\/10.1093\/infdis\/jiac191'>10.1093\/infdis\/jiac191<\/a>. PubMed <a href='http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/35524969'>PMID:35524969<\/a> .<\/li><li>Barroca, V, Racine, C, Pays, L, Fouchet, P, Coureuil, M, Allemand, I <i>et al.<\/i>. The netrin-1 receptor UNC5C contributes to the homeostasis of undifferentiated spermatogonia in adult mice. Stem Cell Res. 2022;60 :102723. doi: <a href='http:\/\/dx.doi.org\/10.1016\/j.scr.2022.102723'>10.1016\/j.scr.2022.102723<\/a>. PubMed <a href='http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/35247845'>PMID:35247845<\/a> .<\/li><li>Barnier, JP, Meyer, J, Kolappan, S, Bouzinba-S\u00e9gard, H, Gesbert, G, Jamet, A <i>et al.<\/i>. The minor pilin PilV provides a conserved adhesion site throughout the antigenically variable meningococcal type IV pilus. Proc Natl Acad Sci U S A. 2021;118 (45):. doi: <a href='http:\/\/dx.doi.org\/10.1073\/pnas.2109364118'>10.1073\/pnas.2109364118<\/a>. PubMed <a href='http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/34725157'>PMID:34725157<\/a> PubMed Central <a href='http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8609321'>PMC8609321<\/a>.<\/li><li>Rytter, H, Jamet, A, Ziveri, J, Ramond, E, Coureuil, M, Lagouge-Roussey, P <i>et al.<\/i>. The pentose phosphate pathway constitutes a major metabolic hub in pathogenic Francisella. PLoS Pathog. 2021;17 (8):e1009326. doi: <a href='http:\/\/dx.doi.org\/10.1371\/journal.ppat.1009326'>10.1371\/journal.ppat.1009326<\/a>. PubMed <a href='http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/34339477'>PMID:34339477<\/a> PubMed Central <a href='http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8360588'>PMC8360588<\/a>.<\/li><li>Ramond, E, Jamet, A, Ding, X, Euphrasie, D, Bouvier, C, Lallemant, L <i>et al.<\/i>. Reactive Oxygen Species-Dependent Innate Immune Mechanisms Control Methicillin-Resistant Staphylococcus aureus Virulence in the <i>Drosophila<\/i> Larval Model. mBio. 2021;12 (3):e0027621. doi: <a href='http:\/\/dx.doi.org\/10.1128\/mBio.00276-21'>10.1128\/mBio.00276-21<\/a>. PubMed <a href='http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/34126772'>PMID:34126772<\/a> PubMed Central <a href='http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8262968'>PMC8262968<\/a>.<\/li><li>Barnier, JP, Euphrasie, D, Join-Lambert, O, Audry, M, Schonherr-Hellec, S, Schmitt, T <i>et al.<\/i>. Type IV pilus retraction enables sustained bacteremia and plays a key role in the outcome of meningococcal sepsis in a humanized mouse model. PLoS Pathog. 2021;17 (2):e1009299. doi: <a href='http:\/\/dx.doi.org\/10.1371\/journal.ppat.1009299'>10.1371\/journal.ppat.1009299<\/a>. PubMed <a href='http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/33592056'>PMID:33592056<\/a> PubMed Central <a href='http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7909687'>PMC7909687<\/a>.<\/li><li>Rytter, H, Jamet, A, Coureuil, M, Charbit, A, Ramond, E. Which Current and Novel Diagnostic Avenues for Bacterial Respiratory Diseases?. Front Microbiol. 2020;11 :616971. doi: <a href='http:\/\/dx.doi.org\/10.3389\/fmicb.2020.616971'>10.3389\/fmicb.2020.616971<\/a>. PubMed <a href='http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/33362754'>PMID:33362754<\/a> PubMed Central <a href='http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7758241'>PMC7758241<\/a>.<\/li><li>Jamet, A, Guglielmini, J, Brancotte, B, Coureuil, M, Euphrasie, D, Meyer, J <i>et al.<\/i>. High-Resolution Typing of <i>Staphylococcus epidermidis<\/i> Based on Core Genome Multilocus Sequence Typing To Investigate the Hospital Spread of Multidrug-Resistant Clones. J Clin Microbiol. 2021;59 (3):. doi: <a href='http:\/\/dx.doi.org\/10.1128\/JCM.02454-20'>10.1128\/JCM.02454-20<\/a>. PubMed <a href='http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/33328176'>PMID:33328176<\/a> PubMed Central <a href='http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8106705'>PMC8106705<\/a>.<\/li><li>Marullo, S, Doly, S, Saha, K, Enslen, H, Scott, MGH, Coureuil, M <i>et al.<\/i>. Mechanical GPCR Activation by Traction Forces Exerted on Receptor <i>N<\/i>-Glycans. ACS Pharmacol Transl Sci. 2020;3 (2):171-178. doi: <a href='http:\/\/dx.doi.org\/10.1021\/acsptsci.9b00106'>10.1021\/acsptsci.9b00106<\/a>. PubMed <a href='http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/32296760'>PMID:32296760<\/a> PubMed Central <a href='http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7155188'>PMC7155188<\/a>.<\/li><li>Dos Santos Souza, I, Ma\u00efssa, N, Ziveri, J, Morand, PC, Coureuil, M, Nassif, X <i>et al.<\/i>. Meningococcal disease: A paradigm of type-IV pilus dependent pathogenesis. Cell Microbiol. 2020;22 (4):e13185. doi: <a href='http:\/\/dx.doi.org\/10.1111\/cmi.13185'>10.1111\/cmi.13185<\/a>. PubMed <a href='http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/32185901'>PMID:32185901<\/a> .<\/li><li>Le Guennec, L, Virion, Z, Bouzinba-S\u00e9gard, H, Robbe-Masselot, C, L\u00e9onard, R, Nassif, X <i>et al.<\/i>. Receptor recognition by meningococcal type IV pili relies on a specific complex <i>N<\/i>-glycan. Proc Natl Acad Sci U S A. 2020;117 (5):2606-2612. doi: <a href='http:\/\/dx.doi.org\/10.1073\/pnas.1919567117'>10.1073\/pnas.1919567117<\/a>. PubMed <a href='http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/31964828'>PMID:31964828<\/a> PubMed Central <a href='http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7007569'>PMC7007569<\/a>.<\/ol><a href='http:\/\/www.ncbi.nlm.nih.gov\/pubmed?term=(coureuil,+mathieu[Author])+AND+Inserm[Affiliation]'>Search PubMed<\/a>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>mathieu.coureuil@inserm.frhttps:\/\/orcid.org\/0000-0001-7655-9685ResearchGate Mathieu Coureuil is team leader. Mathieu Coureuil is Director of Research (DR2) at Inserm. He received his Ph.D. in Cell Biology from University Paris-Sud, France, in 2006. Since then, &#8230;<\/p>\n","protected":false},"author":1,"featured_media":1095,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[18,1],"tags":[],"class_list":["post-308","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-neisseria_meningitidis","category-head"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Mathieu Coureuil - Host Pathogen Biology Team Host Pathogen Integrative Biology<\/title>\n<meta name=\"description\" content=\"Mathieu Coureuil, Host Pathogen Integrative Biology, INEM, Institut Necker Enfants Malades, Paris, Inserm, CNRS, Universit\u00e9 de Paris\" \/>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" 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