{"id":362,"date":"2020-04-10T13:16:23","date_gmt":"2020-04-10T11:16:23","guid":{"rendered":"http:\/\/tnroetk.cluster028.hosting.ovh.net\/?p=362"},"modified":"2025-02-05T22:59:11","modified_gmt":"2025-02-05T21:59:11","slug":"chronic-staphylococcus-aureus-lung-infection-correlates-with-an-increased-intracellular-persistence","status":"publish","type":"post","link":"https:\/\/www.host-pathogen-biology.fr\/index.php\/2020\/04\/10\/chronic-staphylococcus-aureus-lung-infection-correlates-with-an-increased-intracellular-persistence\/","title":{"rendered":"Chronic Staphylococcus Aureus Lung Infection Correlates With an Increased Intracellular Persistence"},"content":{"rendered":"\n<p class=\"wp-block-paragraph\"><strong>Chronic Staphylococcus Aureus Lung Infection Correlates With Proteogenomic and Metabolic Adaptations Leading to an Increased Intracellular Persistence.<\/strong> <a rel=\"noreferrer noopener\" href=\"https:\/\/academic.oup.com\/cid\/article-abstract\/69\/11\/1937\/5308510?redirectedFrom=fulltext\" target=\"_blank\">Tan <em>et al<\/em>, Clin Infect Dis, 69 (11), 1937-1945 2019 Nov 13<\/a><\/p>\n\n\n\n<p class=\"wp-block-paragraph\">News linked to <a href=\"http:\/\/www.posi-lab.fr\/index.php\/2020\/04\/07\/team-2\/\">Alain Charbit<\/a>, <a href=\"http:\/\/www.posi-lab.fr\/index.php\/2020\/04\/09\/mathieu-coureuil\/\">Mathieu Coureuil<\/a> &amp; <a href=\"http:\/\/www.posi-lab.fr\/index.php\/2020\/04\/09\/anne-jamet\/\">Anne Jamet<\/a><\/p>\n\n\n\n<figure class=\"wp-block-image size-medium\"><img loading=\"lazy\" decoding=\"async\" width=\"300\" height=\"110\" src=\"http:\/\/tnroetk.cluster028.hosting.ovh.net\/wp-content\/uploads\/2020\/04\/tan-et-al-300x110.png\" alt=\"\" class=\"wp-image-363\" srcset=\"https:\/\/www.host-pathogen-biology.fr\/wp-content\/uploads\/2020\/04\/tan-et-al-300x110.png 300w, https:\/\/www.host-pathogen-biology.fr\/wp-content\/uploads\/2020\/04\/tan-et-al.png 715w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Background:&nbsp;<\/strong>Chronic lung infection in cystic fibrosis (CF) patients by Staphylococcus aureus is a well-established epidemiological fact. Indeed, S. aureus is the most commonly identified pathogen in the lungs of CF patients. Improving our understanding of the mechanisms associated with the persistence of S. aureus is therefore an important issue.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Methods:&nbsp;<\/strong>We selected pairs of sequential S. aureus isolates from 3 patients with CF and from 1 patient with non-CF chronic lung disease. We used a combination of genomic, proteomic, and metabolomic approaches with functional assays for in-depth characterization of S. aureus long-term persistence.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Results:&nbsp;<\/strong>In this study, we show that late S. aureus isolates from CF patients have an increased ability for intracellular survival in CF bronchial epithelial-F508del cells compared to ancestral early isolates. Importantly, the increased ability to persist intracellularly was confirmed for S. aureus isolates within the own-patient F508del epithelial cells. An increased ability to form biofilm was also demonstrated. Furthermore, we identified the underlying genetic modifications that induce altered protein expression profiles and notable metabolic changes. These modifications affect several metabolic pathways and virulence regulators that could constitute therapeutic targets.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><strong>Conclusions:&nbsp;<\/strong>Our results strongly suggest that the intracellular environment might constitute an important niche of persistence and relapse necessitating adapted antibiotic treatments.<\/p>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Chronic Staphylococcus Aureus Lung Infection Correlates With Proteogenomic and Metabolic Adaptations Leading to an Increased Intracellular Persistence. Tan et al, Clin Infect Dis, 69 (11), 1937-1945 2019 Nov 13 News &#8230;<\/p>\n","protected":false},"author":1,"featured_media":363,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[31,27],"tags":[],"class_list":["post-362","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-award-grant-older-news","category-tsa"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.3 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>Chronic Staphylococcus Aureus Lung Infection Correlates With an Increased Intracellular Persistence<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/www.host-pathogen-biology.fr\/index.php\/2020\/04\/10\/chronic-staphylococcus-aureus-lung-infection-correlates-with-an-increased-intracellular-persistence\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Chronic Staphylococcus Aureus Lung Infection Correlates With an Increased Intracellular Persistence\" \/>\n<meta property=\"og:description\" content=\"Chronic Staphylococcus Aureus Lung Infection Correlates With Proteogenomic and Metabolic Adaptations Leading to an Increased Intracellular Persistence. Tan et al, Clin Infect Dis, 69 (11), 1937-1945 2019 Nov 13 News ...\" \/>\n<meta property=\"og:url\" content=\"https:\/\/www.host-pathogen-biology.fr\/index.php\/2020\/04\/10\/chronic-staphylococcus-aureus-lung-infection-correlates-with-an-increased-intracellular-persistence\/\" \/>\n<meta property=\"og:site_name\" content=\"Host Pathogen Biology Team\" \/>\n<meta property=\"article:published_time\" content=\"2020-04-10T11:16:23+00:00\" \/>\n<meta property=\"article:modified_time\" content=\"2025-02-05T21:59:11+00:00\" \/>\n<meta property=\"og:image\" content=\"http:\/\/www.host-pathogen-biology.fr\/wp-content\/uploads\/2020\/04\/tan-et-al.png\" \/>\n\t<meta property=\"og:image:width\" content=\"715\" \/>\n\t<meta property=\"og:image:height\" content=\"262\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/png\" \/>\n<meta name=\"author\" content=\"admin5413\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:creator\" content=\"@MathieuCoureuil\" \/>\n<meta name=\"twitter:site\" content=\"@MathieuCoureuil\" \/>\n<meta name=\"twitter:label1\" content=\"\u00c9crit par\" \/>\n\t<meta name=\"twitter:data1\" content=\"admin5413\" \/>\n\t<meta name=\"twitter:label2\" content=\"Dur\u00e9e de lecture estim\u00e9e\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\\\/\\\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\\\/\\\/www.host-pathogen-biology.fr\\\/index.php\\\/2020\\\/04\\\/10\\\/chronic-staphylococcus-aureus-lung-infection-correlates-with-an-increased-intracellular-persistence\\\/#article\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.host-pathogen-biology.fr\\\/index.php\\\/2020\\\/04\\\/10\\\/chronic-staphylococcus-aureus-lung-infection-correlates-with-an-increased-intracellular-persistence\\\/\"},\"author\":{\"name\":\"admin5413\",\"@id\":\"https:\\\/\\\/www.host-pathogen-biology.fr\\\/#\\\/schema\\\/person\\\/17f17b8fea7d2fb2c1d0a74958efbe91\"},\"headline\":\"Chronic Staphylococcus Aureus Lung Infection Correlates With an Increased Intracellular Persistence\",\"datePublished\":\"2020-04-10T11:16:23+00:00\",\"dateModified\":\"2025-02-05T21:59:11+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\\\/\\\/www.host-pathogen-biology.fr\\\/index.php\\\/2020\\\/04\\\/10\\\/chronic-staphylococcus-aureus-lung-infection-correlates-with-an-increased-intracellular-persistence\\\/\"},\"wordCount\":256,\"publisher\":{\"@id\":\"https:\\\/\\\/www.host-pathogen-biology.fr\\\/#organization\"},\"image\":{\"@id\":\"https:\\\/\\\/www.host-pathogen-biology.fr\\\/index.php\\\/2020\\\/04\\\/10\\\/chronic-staphylococcus-aureus-lung-infection-correlates-with-an-increased-intracellular-persistence\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.host-pathogen-biology.fr\\\/wp-content\\\/uploads\\\/2020\\\/04\\\/tan-et-al.png\",\"articleSection\":[\"Articles and Grants\",\"Group S. aureus\"],\"inLanguage\":\"fr-FR\"},{\"@type\":\"WebPage\",\"@id\":\"https:\\\/\\\/www.host-pathogen-biology.fr\\\/index.php\\\/2020\\\/04\\\/10\\\/chronic-staphylococcus-aureus-lung-infection-correlates-with-an-increased-intracellular-persistence\\\/\",\"url\":\"https:\\\/\\\/www.host-pathogen-biology.fr\\\/index.php\\\/2020\\\/04\\\/10\\\/chronic-staphylococcus-aureus-lung-infection-correlates-with-an-increased-intracellular-persistence\\\/\",\"name\":\"Chronic Staphylococcus Aureus Lung Infection Correlates With an Increased Intracellular Persistence\",\"isPartOf\":{\"@id\":\"https:\\\/\\\/www.host-pathogen-biology.fr\\\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\\\/\\\/www.host-pathogen-biology.fr\\\/index.php\\\/2020\\\/04\\\/10\\\/chronic-staphylococcus-aureus-lung-infection-correlates-with-an-increased-intracellular-persistence\\\/#primaryimage\"},\"image\":{\"@id\":\"https:\\\/\\\/www.host-pathogen-biology.fr\\\/index.php\\\/2020\\\/04\\\/10\\\/chronic-staphylococcus-aureus-lung-infection-correlates-with-an-increased-intracellular-persistence\\\/#primaryimage\"},\"thumbnailUrl\":\"https:\\\/\\\/www.host-pathogen-biology.fr\\\/wp-content\\\/uploads\\\/2020\\\/04\\\/tan-et-al.png\",\"datePublished\":\"2020-04-10T11:16:23+00:00\",\"dateModified\":\"2025-02-05T21:59:11+00:00\",\"breadcrumb\":{\"@id\":\"https:\\\/\\\/www.host-pathogen-biology.fr\\\/index.php\\\/2020\\\/04\\\/10\\\/chronic-staphylococcus-aureus-lung-infection-correlates-with-an-increased-intracellular-persistence\\\/#breadcrumb\"},\"inLanguage\":\"fr-FR\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\\\/\\\/www.host-pathogen-biology.fr\\\/index.php\\\/2020\\\/04\\\/10\\\/chronic-staphylococcus-aureus-lung-infection-correlates-with-an-increased-intracellular-persistence\\\/\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"fr-FR\",\"@id\":\"https:\\\/\\\/www.host-pathogen-biology.fr\\\/index.php\\\/2020\\\/04\\\/10\\\/chronic-staphylococcus-aureus-lung-infection-correlates-with-an-increased-intracellular-persistence\\\/#primaryimage\",\"url\":\"https:\\\/\\\/www.host-pathogen-biology.fr\\\/wp-content\\\/uploads\\\/2020\\\/04\\\/tan-et-al.png\",\"contentUrl\":\"https:\\\/\\\/www.host-pathogen-biology.fr\\\/wp-content\\\/uploads\\\/2020\\\/04\\\/tan-et-al.png\",\"width\":715,\"height\":262},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\\\/\\\/www.host-pathogen-biology.fr\\\/index.php\\\/2020\\\/04\\\/10\\\/chronic-staphylococcus-aureus-lung-infection-correlates-with-an-increased-intracellular-persistence\\\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Accueil\",\"item\":\"https:\\\/\\\/www.host-pathogen-biology.fr\\\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Chronic Staphylococcus Aureus Lung Infection Correlates With an Increased Intracellular Persistence\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\\\/\\\/www.host-pathogen-biology.fr\\\/#website\",\"url\":\"https:\\\/\\\/www.host-pathogen-biology.fr\\\/\",\"name\":\"Pathogenesis of Systemic Infection\",\"description\":\"Host Pathogen Biology Team\",\"publisher\":{\"@id\":\"https:\\\/\\\/www.host-pathogen-biology.fr\\\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\\\/\\\/www.host-pathogen-biology.fr\\\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"fr-FR\"},{\"@type\":\"Organization\",\"@id\":\"https:\\\/\\\/www.host-pathogen-biology.fr\\\/#organization\",\"name\":\"pathogenesis of systemic infection\",\"url\":\"https:\\\/\\\/www.host-pathogen-biology.fr\\\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"fr-FR\",\"@id\":\"https:\\\/\\\/www.host-pathogen-biology.fr\\\/#\\\/schema\\\/logo\\\/image\\\/\",\"url\":\"http:\\\/\\\/www.posi-lab.fr\\\/wp-content\\\/uploads\\\/2020\\\/04\\\/PoSI-e1586270099534.jpg\",\"contentUrl\":\"http:\\\/\\\/www.posi-lab.fr\\\/wp-content\\\/uploads\\\/2020\\\/04\\\/PoSI-e1586270099534.jpg\",\"width\":100,\"height\":104,\"caption\":\"pathogenesis of systemic infection\"},\"image\":{\"@id\":\"https:\\\/\\\/www.host-pathogen-biology.fr\\\/#\\\/schema\\\/logo\\\/image\\\/\"},\"sameAs\":[\"https:\\\/\\\/x.com\\\/MathieuCoureuil\"]},{\"@type\":\"Person\",\"@id\":\"https:\\\/\\\/www.host-pathogen-biology.fr\\\/#\\\/schema\\\/person\\\/17f17b8fea7d2fb2c1d0a74958efbe91\",\"name\":\"admin5413\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"fr-FR\",\"@id\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/59784dd5f63304756b314e622a00a02a8a5d1cc81bc2c849cdaca23f8d94e800?s=96&d=mm&r=g\",\"url\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/59784dd5f63304756b314e622a00a02a8a5d1cc81bc2c849cdaca23f8d94e800?s=96&d=mm&r=g\",\"contentUrl\":\"https:\\\/\\\/secure.gravatar.com\\\/avatar\\\/59784dd5f63304756b314e622a00a02a8a5d1cc81bc2c849cdaca23f8d94e800?s=96&d=mm&r=g\",\"caption\":\"admin5413\"}}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Chronic Staphylococcus Aureus Lung Infection Correlates With an Increased Intracellular Persistence","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/www.host-pathogen-biology.fr\/index.php\/2020\/04\/10\/chronic-staphylococcus-aureus-lung-infection-correlates-with-an-increased-intracellular-persistence\/","og_locale":"fr_FR","og_type":"article","og_title":"Chronic Staphylococcus Aureus Lung Infection Correlates With an Increased Intracellular Persistence","og_description":"Chronic Staphylococcus Aureus Lung Infection Correlates With Proteogenomic and Metabolic Adaptations Leading to an Increased Intracellular Persistence. Tan et al, Clin Infect Dis, 69 (11), 1937-1945 2019 Nov 13 News ...","og_url":"https:\/\/www.host-pathogen-biology.fr\/index.php\/2020\/04\/10\/chronic-staphylococcus-aureus-lung-infection-correlates-with-an-increased-intracellular-persistence\/","og_site_name":"Host Pathogen Biology Team","article_published_time":"2020-04-10T11:16:23+00:00","article_modified_time":"2025-02-05T21:59:11+00:00","og_image":[{"width":715,"height":262,"url":"http:\/\/www.host-pathogen-biology.fr\/wp-content\/uploads\/2020\/04\/tan-et-al.png","type":"image\/png"}],"author":"admin5413","twitter_card":"summary_large_image","twitter_creator":"@MathieuCoureuil","twitter_site":"@MathieuCoureuil","twitter_misc":{"\u00c9crit par":"admin5413","Dur\u00e9e de lecture estim\u00e9e":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/www.host-pathogen-biology.fr\/index.php\/2020\/04\/10\/chronic-staphylococcus-aureus-lung-infection-correlates-with-an-increased-intracellular-persistence\/#article","isPartOf":{"@id":"https:\/\/www.host-pathogen-biology.fr\/index.php\/2020\/04\/10\/chronic-staphylococcus-aureus-lung-infection-correlates-with-an-increased-intracellular-persistence\/"},"author":{"name":"admin5413","@id":"https:\/\/www.host-pathogen-biology.fr\/#\/schema\/person\/17f17b8fea7d2fb2c1d0a74958efbe91"},"headline":"Chronic Staphylococcus Aureus Lung Infection Correlates With an Increased Intracellular Persistence","datePublished":"2020-04-10T11:16:23+00:00","dateModified":"2025-02-05T21:59:11+00:00","mainEntityOfPage":{"@id":"https:\/\/www.host-pathogen-biology.fr\/index.php\/2020\/04\/10\/chronic-staphylococcus-aureus-lung-infection-correlates-with-an-increased-intracellular-persistence\/"},"wordCount":256,"publisher":{"@id":"https:\/\/www.host-pathogen-biology.fr\/#organization"},"image":{"@id":"https:\/\/www.host-pathogen-biology.fr\/index.php\/2020\/04\/10\/chronic-staphylococcus-aureus-lung-infection-correlates-with-an-increased-intracellular-persistence\/#primaryimage"},"thumbnailUrl":"https:\/\/www.host-pathogen-biology.fr\/wp-content\/uploads\/2020\/04\/tan-et-al.png","articleSection":["Articles and Grants","Group S. aureus"],"inLanguage":"fr-FR"},{"@type":"WebPage","@id":"https:\/\/www.host-pathogen-biology.fr\/index.php\/2020\/04\/10\/chronic-staphylococcus-aureus-lung-infection-correlates-with-an-increased-intracellular-persistence\/","url":"https:\/\/www.host-pathogen-biology.fr\/index.php\/2020\/04\/10\/chronic-staphylococcus-aureus-lung-infection-correlates-with-an-increased-intracellular-persistence\/","name":"Chronic Staphylococcus Aureus Lung Infection Correlates With an Increased Intracellular Persistence","isPartOf":{"@id":"https:\/\/www.host-pathogen-biology.fr\/#website"},"primaryImageOfPage":{"@id":"https:\/\/www.host-pathogen-biology.fr\/index.php\/2020\/04\/10\/chronic-staphylococcus-aureus-lung-infection-correlates-with-an-increased-intracellular-persistence\/#primaryimage"},"image":{"@id":"https:\/\/www.host-pathogen-biology.fr\/index.php\/2020\/04\/10\/chronic-staphylococcus-aureus-lung-infection-correlates-with-an-increased-intracellular-persistence\/#primaryimage"},"thumbnailUrl":"https:\/\/www.host-pathogen-biology.fr\/wp-content\/uploads\/2020\/04\/tan-et-al.png","datePublished":"2020-04-10T11:16:23+00:00","dateModified":"2025-02-05T21:59:11+00:00","breadcrumb":{"@id":"https:\/\/www.host-pathogen-biology.fr\/index.php\/2020\/04\/10\/chronic-staphylococcus-aureus-lung-infection-correlates-with-an-increased-intracellular-persistence\/#breadcrumb"},"inLanguage":"fr-FR","potentialAction":[{"@type":"ReadAction","target":["https:\/\/www.host-pathogen-biology.fr\/index.php\/2020\/04\/10\/chronic-staphylococcus-aureus-lung-infection-correlates-with-an-increased-intracellular-persistence\/"]}]},{"@type":"ImageObject","inLanguage":"fr-FR","@id":"https:\/\/www.host-pathogen-biology.fr\/index.php\/2020\/04\/10\/chronic-staphylococcus-aureus-lung-infection-correlates-with-an-increased-intracellular-persistence\/#primaryimage","url":"https:\/\/www.host-pathogen-biology.fr\/wp-content\/uploads\/2020\/04\/tan-et-al.png","contentUrl":"https:\/\/www.host-pathogen-biology.fr\/wp-content\/uploads\/2020\/04\/tan-et-al.png","width":715,"height":262},{"@type":"BreadcrumbList","@id":"https:\/\/www.host-pathogen-biology.fr\/index.php\/2020\/04\/10\/chronic-staphylococcus-aureus-lung-infection-correlates-with-an-increased-intracellular-persistence\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Accueil","item":"https:\/\/www.host-pathogen-biology.fr\/"},{"@type":"ListItem","position":2,"name":"Chronic Staphylococcus Aureus Lung Infection Correlates With an Increased Intracellular Persistence"}]},{"@type":"WebSite","@id":"https:\/\/www.host-pathogen-biology.fr\/#website","url":"https:\/\/www.host-pathogen-biology.fr\/","name":"Pathogenesis of Systemic Infection","description":"Host Pathogen Biology Team","publisher":{"@id":"https:\/\/www.host-pathogen-biology.fr\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/www.host-pathogen-biology.fr\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"fr-FR"},{"@type":"Organization","@id":"https:\/\/www.host-pathogen-biology.fr\/#organization","name":"pathogenesis of systemic infection","url":"https:\/\/www.host-pathogen-biology.fr\/","logo":{"@type":"ImageObject","inLanguage":"fr-FR","@id":"https:\/\/www.host-pathogen-biology.fr\/#\/schema\/logo\/image\/","url":"http:\/\/www.posi-lab.fr\/wp-content\/uploads\/2020\/04\/PoSI-e1586270099534.jpg","contentUrl":"http:\/\/www.posi-lab.fr\/wp-content\/uploads\/2020\/04\/PoSI-e1586270099534.jpg","width":100,"height":104,"caption":"pathogenesis of systemic infection"},"image":{"@id":"https:\/\/www.host-pathogen-biology.fr\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/x.com\/MathieuCoureuil"]},{"@type":"Person","@id":"https:\/\/www.host-pathogen-biology.fr\/#\/schema\/person\/17f17b8fea7d2fb2c1d0a74958efbe91","name":"admin5413","image":{"@type":"ImageObject","inLanguage":"fr-FR","@id":"https:\/\/secure.gravatar.com\/avatar\/59784dd5f63304756b314e622a00a02a8a5d1cc81bc2c849cdaca23f8d94e800?s=96&d=mm&r=g","url":"https:\/\/secure.gravatar.com\/avatar\/59784dd5f63304756b314e622a00a02a8a5d1cc81bc2c849cdaca23f8d94e800?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/59784dd5f63304756b314e622a00a02a8a5d1cc81bc2c849cdaca23f8d94e800?s=96&d=mm&r=g","caption":"admin5413"}}]}},"_links":{"self":[{"href":"https:\/\/www.host-pathogen-biology.fr\/index.php\/wp-json\/wp\/v2\/posts\/362","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.host-pathogen-biology.fr\/index.php\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.host-pathogen-biology.fr\/index.php\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.host-pathogen-biology.fr\/index.php\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.host-pathogen-biology.fr\/index.php\/wp-json\/wp\/v2\/comments?post=362"}],"version-history":[{"count":5,"href":"https:\/\/www.host-pathogen-biology.fr\/index.php\/wp-json\/wp\/v2\/posts\/362\/revisions"}],"predecessor-version":[{"id":689,"href":"https:\/\/www.host-pathogen-biology.fr\/index.php\/wp-json\/wp\/v2\/posts\/362\/revisions\/689"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.host-pathogen-biology.fr\/index.php\/wp-json\/wp\/v2\/media\/363"}],"wp:attachment":[{"href":"https:\/\/www.host-pathogen-biology.fr\/index.php\/wp-json\/wp\/v2\/media?parent=362"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.host-pathogen-biology.fr\/index.php\/wp-json\/wp\/v2\/categories?post=362"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.host-pathogen-biology.fr\/index.php\/wp-json\/wp\/v2\/tags?post=362"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}