{"id":49,"date":"2020-04-07T17:44:51","date_gmt":"2020-04-07T15:44:51","guid":{"rendered":"http:\/\/tnroetk.cluster028.hosting.ovh.net\/?p=49"},"modified":"2025-02-03T21:34:49","modified_gmt":"2025-02-03T20:34:49","slug":"xavier-nassif","status":"publish","type":"post","link":"https:\/\/www.host-pathogen-biology.fr\/index.php\/2020\/04\/07\/xavier-nassif\/","title":{"rendered":"Xavier Nassif"},"content":{"rendered":"\n<p class=\"has-text-align-left\">Xavier Nassif, M.D-PhD, is Professor of Microbiology at the Medical School Paris Descartes. He earned his Medical Degree in 1987 and completed his PhD at Institut Pasteur in 1989. Following a postdoctoral fellowship, he joined the Faculty of Medicine of Paris Descartes in 1992. Xavier is former head of the Clinical Microbiology Laboratory at Hospital Necker, former head of Institut Pasteur Lille. Currently, Xavier co-leads the team alongside Alain Charbit.<br><\/p>\n\n\n\n<figure class=\"wp-block-image\"><img loading=\"lazy\" decoding=\"async\" width=\"128\" height=\"128\" src=\"http:\/\/tnroetk.cluster028.hosting.ovh.net\/wp-content\/uploads\/2020\/04\/nassif.jpg\" alt=\"\" class=\"wp-image-64\" srcset=\"https:\/\/www.host-pathogen-biology.fr\/wp-content\/uploads\/2020\/04\/nassif.jpg 128w, https:\/\/www.host-pathogen-biology.fr\/wp-content\/uploads\/2020\/04\/nassif-60x60.jpg 60w\" sizes=\"auto, (max-width: 128px) 100vw, 128px\" \/><\/figure>\n\n\n\n<hr class=\"wp-block-separator has-css-opacity\"\/>\n\n\n\n<div class=\"wp-block-columns is-layout-flex wp-container-core-columns-is-layout-9d6595d7 wp-block-columns-is-layout-flex\">\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:66.66%\">\n<p class=\"has-very-dark-gray-color has-text-color has-medium-font-size\"><strong>Last News of the Lab<\/strong><br><div class=\"pt-cv-wrapper\"><div class=\"pt-cv-view pt-cv-grid pt-cv-colsys\" id=\"pt-cv-view-f1300adszx\"><div data-id=\"pt-cv-page-1\" class=\"pt-cv-page\" data-cvc=\"1\"><div class=\"col-md-12 col-sm-12 col-xs-12 pt-cv-content-item pt-cv-2-col\" ><div class='pt-cv-ifield'><a href=\"https:\/\/www.host-pathogen-biology.fr\/index.php\/2026\/03\/10\/vulgarisation-scientifique-microcros\/\" class=\"_self pt-cv-href-thumbnail pt-cv-thumb-left\" target=\"_self\" ><img loading=\"lazy\" decoding=\"async\" width=\"150\" height=\"150\" src=\"https:\/\/www.host-pathogen-biology.fr\/wp-content\/uploads\/2026\/03\/MicroCrocs-150x150.jpg\" class=\"pt-cv-thumbnail pull-left\" alt=\"\" \/><\/a>\n<h4 class=\"pt-cv-title\"><a href=\"https:\/\/www.host-pathogen-biology.fr\/index.php\/2026\/03\/10\/vulgarisation-scientifique-microcros\/\" class=\"_self\" target=\"_self\" >Vulgarisation scientifique @MicroCros<\/a><\/h4>\n<div class=\"pt-cv-content\">10\/03\/2026 Les bact\u00e9ries manipulent nos cellules gr\u00e2ce \u00e0 la physique Audrey Laurent Granger Les bact\u00e9ries sont partout, y compris \u00e0 ...<br \/><div class=\"pt-cv-rmwrap\"><a href=\"https:\/\/www.host-pathogen-biology.fr\/index.php\/2026\/03\/10\/vulgarisation-scientifique-microcros\/\" class=\"_self pt-cv-readmore btn btn-success\" target=\"_self\">Lire La Suite\u2026<\/a><\/div><\/div><\/div><\/div>\n<div class=\"col-md-12 col-sm-12 col-xs-12 pt-cv-content-item pt-cv-2-col\" ><div class='pt-cv-ifield'><a href=\"https:\/\/www.host-pathogen-biology.fr\/index.php\/2025\/12\/20\/the-mda-promotes-bacterial-colonisation\/\" class=\"_self pt-cv-href-thumbnail pt-cv-thumb-left\" target=\"_self\" ><img loading=\"lazy\" decoding=\"async\" width=\"150\" height=\"150\" src=\"https:\/\/www.host-pathogen-biology.fr\/wp-content\/uploads\/2025\/12\/Nat-commun-150x150.jpg\" class=\"pt-cv-thumbnail pull-left\" alt=\"\" \/><\/a>\n<h4 class=\"pt-cv-title\"><a href=\"https:\/\/www.host-pathogen-biology.fr\/index.php\/2025\/12\/20\/the-mda-promotes-bacterial-colonisation\/\" class=\"_self\" target=\"_self\" >The MDA promotes bacterial colonisation by selecting hyperadhesive pili variants<\/a><\/h4>\n<div class=\"pt-cv-content\">20\/12\/2025 Neisseria meningitidis filamentous phage MDA promotes colonisation by selecting hyperadhesive pili variants Cl\u00e9mence Mouville,\u00a0Antoine Brizard,\u00a0Morgane Wuckelt,\u00a0M\u00e9lanie Montabord,\u00a0Herv\u00e9 L\u00e9cuyer,\u00a0Julie Meyer,\u00a0Anne ...<br \/><div class=\"pt-cv-rmwrap\"><a href=\"https:\/\/www.host-pathogen-biology.fr\/index.php\/2025\/12\/20\/the-mda-promotes-bacterial-colonisation\/\" class=\"_self pt-cv-readmore btn btn-success\" target=\"_self\">Lire La Suite\u2026<\/a><\/div><\/div><\/div><\/div>\n<div class=\"col-md-12 col-sm-12 col-xs-12 pt-cv-content-item pt-cv-2-col\" ><div class='pt-cv-ifield'><a href=\"https:\/\/www.host-pathogen-biology.fr\/index.php\/2025\/12\/05\/meningococci-reshape-host-membranes-to-recruit-their-own-signaling-receptors\/\" class=\"_self pt-cv-href-thumbnail pt-cv-thumb-left\" target=\"_self\" ><img loading=\"lazy\" decoding=\"async\" width=\"150\" height=\"150\" src=\"https:\/\/www.host-pathogen-biology.fr\/wp-content\/uploads\/2025\/12\/Nat-commun-150x150.jpg\" class=\"pt-cv-thumbnail pull-left\" alt=\"\" \/><\/a>\n<h4 class=\"pt-cv-title\"><a href=\"https:\/\/www.host-pathogen-biology.fr\/index.php\/2025\/12\/05\/meningococci-reshape-host-membranes-to-recruit-their-own-signaling-receptors\/\" class=\"_self\" target=\"_self\" >Meningococci reshape host membranes to recruit their own signaling receptors<\/a><\/h4>\n<div class=\"pt-cv-content\">05\/12\/2025. Meningococci drive host membrane tubulation to recruit their signaling receptors Audrey Laurent-Granger, K\u00e9vin Sollier, Bruno Saubamea, Virginie Mignon, Nicolas ...<br \/><div class=\"pt-cv-rmwrap\"><a href=\"https:\/\/www.host-pathogen-biology.fr\/index.php\/2025\/12\/05\/meningococci-reshape-host-membranes-to-recruit-their-own-signaling-receptors\/\" class=\"_self pt-cv-readmore btn btn-success\" target=\"_self\">Lire La Suite\u2026<\/a><\/div><\/div><\/div><\/div>\n<div class=\"col-md-12 col-sm-12 col-xs-12 pt-cv-content-item pt-cv-2-col\" ><div class='pt-cv-ifield'><a href=\"https:\/\/www.host-pathogen-biology.fr\/index.php\/2025\/10\/01\/newcomers-in-the-lab\/\" class=\"_self pt-cv-href-thumbnail pt-cv-thumb-left\" target=\"_self\" ><img loading=\"lazy\" decoding=\"async\" width=\"150\" height=\"150\" src=\"https:\/\/www.host-pathogen-biology.fr\/wp-content\/uploads\/2025\/02\/HPIB-logo-news-150x150.png\" class=\"pt-cv-thumbnail pull-left\" alt=\"\" \/><\/a>\n<h4 class=\"pt-cv-title\"><a href=\"https:\/\/www.host-pathogen-biology.fr\/index.php\/2025\/10\/01\/newcomers-in-the-lab\/\" class=\"_self\" target=\"_self\" >Newcomers in the Lab<\/a><\/h4>\n<div class=\"pt-cv-content\">01\/10\/2025. It's time to welcome Five new lab members: Anne-Aur\u00e9lie Lopes, MD, PhD, HDR. Anne Aur\u00e9lie join the lab and ...<br \/><div class=\"pt-cv-rmwrap\"><a href=\"https:\/\/www.host-pathogen-biology.fr\/index.php\/2025\/10\/01\/newcomers-in-the-lab\/\" class=\"_self pt-cv-readmore btn btn-success\" target=\"_self\">Lire La Suite\u2026<\/a><\/div><\/div><\/div><\/div><\/div><\/div><\/div><\/p>\n<\/div>\n\n\n\n<div class=\"wp-block-column is-layout-flow wp-block-column-is-layout-flow\" style=\"flex-basis:33.33%\">\n<p class=\"has-very-dark-gray-color has-text-color has-medium-font-size\"><strong>Team Members<br><\/strong><ul class=\"lcp_catlist\" id=\"lcp_instance_0\"><li><a href=\"https:\/\/www.host-pathogen-biology.fr\/index.php\/2020\/04\/09\/mathieu-coureuil\/\">Mathieu Coureuil<\/a><\/li><li><a href=\"https:\/\/www.host-pathogen-biology.fr\/index.php\/2020\/04\/09\/emmanuelle-bille\/\">Emmanuelle Bille<\/a><\/li><li class=\"current\"><a href=\"https:\/\/www.host-pathogen-biology.fr\/index.php\/2020\/04\/07\/xavier-nassif\/\">Xavier Nassif<\/a><\/li><li><a href=\"https:\/\/www.host-pathogen-biology.fr\/index.php\/2025\/11\/03\/mariam-wehbi\/\">Mariam Wehbi<\/a><\/li><li><a href=\"https:\/\/www.host-pathogen-biology.fr\/index.php\/2023\/01\/25\/morgane-wuckelt\/\">Morgane Wuckelt<\/a><\/li><li><a href=\"https:\/\/www.host-pathogen-biology.fr\/index.php\/2025\/02\/04\/lison-reboul\/\">Lison Reboul<\/a><\/li><li><a href=\"https:\/\/www.host-pathogen-biology.fr\/index.php\/2023\/01\/26\/julie-brousseau\/\">Julie Brousseau<\/a><\/li><\/ul><\/p>\n<\/div>\n<\/div>\n\n\n\n<hr class=\"wp-block-separator has-css-opacity\"\/>\n\n\n\n<p class=\"has-very-dark-gray-color has-text-color has-medium-font-size\"><strong>Last 25 Publications<\/strong> <\/p>\n\n\n\n<!-- load from cache<br> --><ol><li>Mouville, C, Brizard, A, Wuckelt, M, Montabord, M, L\u00e9cuyer, H, Meyer, J <i>et al.<\/i>. Neisseria meningitidis filamentous phage MDA promotes colonisation by selecting hyperadhesive pili variants. Nat Commun. 2025;17 (1):744. doi: <a href='http:\/\/dx.doi.org\/10.1038\/s41467-025-67441-w'>10.1038\/s41467-025-67441-w<\/a>. PubMed <a href='http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/41422109'>PMID:41422109<\/a> PubMed Central <a href='http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC12819557'>PMC12819557<\/a>.<\/li><li>B\u00f6hning, J, Graham, M, Coureuil, M, Tarafder, AK, Meyer, J, Nassif, X <i>et al.<\/i>. Structure of the virulence-associated <i>Neisseria meningitidis<\/i> filamentous bacteriophage MDA&#x3a6;. Proc Natl Acad Sci U S A. 2025;122 (25):e2420157122. doi: <a href='http:\/\/dx.doi.org\/10.1073\/pnas.2420157122'>10.1073\/pnas.2420157122<\/a>. PubMed <a href='http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/40540604'>PMID:40540604<\/a> PubMed Central <a href='http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC12207478'>PMC12207478<\/a>.<\/li><li>Wuckelt, M, Laurent, A, Mouville, C, Meyer, J, Jamet, A, Lecuyer, H <i>et al.<\/i>. Expanding the genetic toolbox for <i>Neisseria meningitidis<\/i> with efficient tools for unmarked gene editing, complementation, and labeling. Appl Environ Microbiol. 2024;90 (9):e0088024. doi: <a href='http:\/\/dx.doi.org\/10.1128\/aem.00880-24'>10.1128\/aem.00880-24<\/a>. PubMed <a href='http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/39140741'>PMID:39140741<\/a> PubMed Central <a href='http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC11409642'>PMC11409642<\/a>.<\/li><li>Ziveri, J, Le Guennec, L, Dos Santos Souza, I, Barnier, JP, Walter, SM, Diallo, Y <i>et al.<\/i>. Angiopoietin-like 4 protects against endothelial dysfunction during bacterial sepsis. Nat Microbiol. 2024;9 (9):2434-2447. doi: <a href='http:\/\/dx.doi.org\/10.1038\/s41564-024-01760-4'>10.1038\/s41564-024-01760-4<\/a>. PubMed <a href='http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/39103571'>PMID:39103571<\/a> .<\/li><li>Fourgeaud, J, Regnault, B, Ok, V, Da Rocha, N, Sitterl\u00e9, \u00c9, Mekouar, M <i>et al.<\/i>. Performance of clinical metagenomics in France: a prospective observational study. Lancet Microbe. 2024;5 (1):e52-e61. doi: <a href='http:\/\/dx.doi.org\/10.1016\/S2666-5247(23)00244-6'>10.1016\/S2666-5247(23)00244-6<\/a>. PubMed <a href='http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/38048804'>PMID:38048804<\/a> .<\/li><li>Wu, S, Coureuil, M, Nassif, X, Tautz, L. NMA1982 is a Novel Phosphatase and Potential Virulence Factor in <i>Neisseria meningitidis<\/i>. bioRxiv. 2023; :. doi: <a href='http:\/\/dx.doi.org\/10.1101\/2023.05.23.541968'>10.1101\/2023.05.23.541968<\/a>. PubMed <a href='http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/37292688'>PMID:37292688<\/a> PubMed Central <a href='http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC10245925'>PMC10245925<\/a>.<\/li><li>Sch\u00f6nherr-Hellec, S, Chatzopoulou, E, Barnier, JP, Atlas, Y, Dupichaud, S, Guilbert, T <i>et al.<\/i>. Implantation of engineered human microvasculature to study human infectious diseases in mouse models. iScience. 2023;26 (4):106286. doi: <a href='http:\/\/dx.doi.org\/10.1016\/j.isci.2023.106286'>10.1016\/j.isci.2023.106286<\/a>. PubMed <a href='http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/36942053'>PMID:36942053<\/a> PubMed Central <a href='http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC10024136'>PMC10024136<\/a>.<\/li><li>Ramond, E, Lepissier, A, Ding, X, Bouvier, C, Tan, X, Euphrasie, D <i>et al.<\/i>. Lung-Adapted Staphylococcus aureus Isolates With Dysfunctional Agr System Trigger a Proinflammatory Response. J Infect Dis. 2022;226 (7):1276-1285. doi: <a href='http:\/\/dx.doi.org\/10.1093\/infdis\/jiac191'>10.1093\/infdis\/jiac191<\/a>. PubMed <a href='http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/35524969'>PMID:35524969<\/a> .<\/li><li>Barnier, JP, Meyer, J, Kolappan, S, Bouzinba-S\u00e9gard, H, Gesbert, G, Jamet, A <i>et al.<\/i>. The minor pilin PilV provides a conserved adhesion site throughout the antigenically variable meningococcal type IV pilus. Proc Natl Acad Sci U S A. 2021;118 (45):. doi: <a href='http:\/\/dx.doi.org\/10.1073\/pnas.2109364118'>10.1073\/pnas.2109364118<\/a>. PubMed <a href='http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/34725157'>PMID:34725157<\/a> PubMed Central <a href='http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8609321'>PMC8609321<\/a>.<\/li><li>Barnier, JP, Euphrasie, D, Join-Lambert, O, Audry, M, Schonherr-Hellec, S, Schmitt, T <i>et al.<\/i>. Type IV pilus retraction enables sustained bacteremia and plays a key role in the outcome of meningococcal sepsis in a humanized mouse model. PLoS Pathog. 2021;17 (2):e1009299. doi: <a href='http:\/\/dx.doi.org\/10.1371\/journal.ppat.1009299'>10.1371\/journal.ppat.1009299<\/a>. PubMed <a href='http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/33592056'>PMID:33592056<\/a> PubMed Central <a href='http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7909687'>PMC7909687<\/a>.<\/li><li>Jamet, A, Guglielmini, J, Brancotte, B, Coureuil, M, Euphrasie, D, Meyer, J <i>et al.<\/i>. High-Resolution Typing of <i>Staphylococcus epidermidis<\/i> Based on Core Genome Multilocus Sequence Typing To Investigate the Hospital Spread of Multidrug-Resistant Clones. J Clin Microbiol. 2021;59 (3):. doi: <a href='http:\/\/dx.doi.org\/10.1128\/JCM.02454-20'>10.1128\/JCM.02454-20<\/a>. PubMed <a href='http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/33328176'>PMID:33328176<\/a> PubMed Central <a href='http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC8106705'>PMC8106705<\/a>.<\/li><li>Dos Santos Souza, I, Ma\u00efssa, N, Ziveri, J, Morand, PC, Coureuil, M, Nassif, X <i>et al.<\/i>. Meningococcal disease: A paradigm of type-IV pilus dependent pathogenesis. Cell Microbiol. 2020;22 (4):e13185. doi: <a href='http:\/\/dx.doi.org\/10.1111\/cmi.13185'>10.1111\/cmi.13185<\/a>. PubMed <a href='http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/32185901'>PMID:32185901<\/a> .<\/li><li>Le Guennec, L, Virion, Z, Bouzinba-S\u00e9gard, H, Robbe-Masselot, C, L\u00e9onard, R, Nassif, X <i>et al.<\/i>. Receptor recognition by meningococcal type IV pili relies on a specific complex <i>N<\/i>-glycan. Proc Natl Acad Sci U S A. 2020;117 (5):2606-2612. doi: <a href='http:\/\/dx.doi.org\/10.1073\/pnas.1919567117'>10.1073\/pnas.1919567117<\/a>. PubMed <a href='http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/31964828'>PMID:31964828<\/a> PubMed Central <a href='http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC7007569'>PMC7007569<\/a>.<\/li><li>Audry, M, Robbe-Masselot, C, Barnier, JP, Gachet, B, Saubam\u00e9a, B, Schmitt, A <i>et al.<\/i>. Airway Mucus Restricts Neisseria meningitidis Away from Nasopharyngeal Epithelial Cells and Protects the Mucosa from Inflammation. mSphere. 2019;4 (6):. doi: <a href='http:\/\/dx.doi.org\/10.1128\/mSphere.00494-19'>10.1128\/mSphere.00494-19<\/a>. PubMed <a href='http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/31801841'>PMID:31801841<\/a> PubMed Central <a href='http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6893211'>PMC6893211<\/a>.<\/li><li>Simonin, J, Bille, E, Crambert, G, Noel, S, Dreano, E, Edwards, A <i>et al.<\/i>. Author Correction: Airway surface liquid acidification initiates host defense abnormalities in Cystic Fibrosis. Sci Rep. 2019;9 (1):17535. doi: <a href='http:\/\/dx.doi.org\/10.1038\/s41598-019-54253-4'>10.1038\/s41598-019-54253-4<\/a>. PubMed <a href='http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/31754179'>PMID:31754179<\/a> PubMed Central <a href='http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6872590'>PMC6872590<\/a>.<\/li><li>Le Guennec, L, Coureuil, M, Nassif, X, Bourdoulous, S. Strategies used by bacterial pathogens to cross the blood-brain barrier. Cell Microbiol. 2020;22 (1):e13132. doi: <a href='http:\/\/dx.doi.org\/10.1111\/cmi.13132'>10.1111\/cmi.13132<\/a>. PubMed <a href='http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/31658405'>PMID:31658405<\/a> .<\/li><li>Virion, Z, Doly, S, Saha, K, Lambert, M, Guillonneau, F, Bied, C <i>et al.<\/i>. Sialic acid mediated mechanical activation of &#x3b2;<sub>2<\/sub> adrenergic receptors by bacterial pili. Nat Commun. 2019;10 (1):4752. doi: <a href='http:\/\/dx.doi.org\/10.1038\/s41467-019-12685-6'>10.1038\/s41467-019-12685-6<\/a>. PubMed <a href='http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/31628314'>PMID:31628314<\/a> PubMed Central <a href='http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6800425'>PMC6800425<\/a>.<\/li><li>Tan, X, Ramond, E, Jamet, A, Barnier, JP, Decaux-Tramoni, B, Dupuis, M <i>et al.<\/i>. Transketolase of Staphylococcus aureus in the Control of Master Regulators of Stress Response During Infection. J Infect Dis. 2019;220 (12):1967-1976. doi: <a href='http:\/\/dx.doi.org\/10.1093\/infdis\/jiz404'>10.1093\/infdis\/jiz404<\/a>. PubMed <a href='http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/31420648'>PMID:31420648<\/a> .<\/li><li>Coureuil, M, Jamet, A, Bille, E, L\u00e9cuyer, H, Bourdoulous, S, Nassif, X <i>et al.<\/i>. Molecular interactions between Neisseria meningitidis and its human host. Cell Microbiol. 2019;21 (11):e13063. doi: <a href='http:\/\/dx.doi.org\/10.1111\/cmi.13063'>10.1111\/cmi.13063<\/a>. PubMed <a href='http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/31167044'>PMID:31167044<\/a> PubMed Central <a href='http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6899865'>PMC6899865<\/a>.<\/li><li>Simonin, J, Bille, E, Crambert, G, Noel, S, Dreano, E, Edwards, A <i>et al.<\/i>. Airway surface liquid acidification initiates host defense abnormalities in Cystic Fibrosis. Sci Rep. 2019;9 (1):6516. doi: <a href='http:\/\/dx.doi.org\/10.1038\/s41598-019-42751-4'>10.1038\/s41598-019-42751-4<\/a>. PubMed <a href='http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/31019198'>PMID:31019198<\/a> PubMed Central <a href='http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6482305'>PMC6482305<\/a>.<\/li><li>Vidal, C, Moulin, F, Nassif, X, Galmiche, L, Borgel, D, Charbit, A <i>et al.<\/i>. Fulminant arterial vasculitis as an unusual complication of disseminated staphylococcal disease due to the emerging CC1 methicillin-susceptible Staphylococcus aureus clone: a case report. BMC Infect Dis. 2019;19 (1):302. doi: <a href='http:\/\/dx.doi.org\/10.1186\/s12879-019-3933-3'>10.1186\/s12879-019-3933-3<\/a>. PubMed <a href='http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/30943907'>PMID:30943907<\/a> PubMed Central <a href='http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6446405'>PMC6446405<\/a>.<\/li><li>Denis, K, Le Bris, M, Le Guennec, L, Barnier, JP, Faure, C, Gouge, A <i>et al.<\/i>. Targeting Type IV pili as an antivirulence strategy against invasive meningococcal disease. Nat Microbiol. 2019;4 (6):972-984. doi: <a href='http:\/\/dx.doi.org\/10.1038\/s41564-019-0395-8'>10.1038\/s41564-019-0395-8<\/a>. PubMed <a href='http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/30911127'>PMID:30911127<\/a> .<\/li><li>Tan, X, Coureuil, M, Ramond, E, Euphrasie, D, Dupuis, M, Tros, F <i>et al.<\/i>. Chronic Staphylococcus aureus Lung Infection Correlates With Proteogenomic and Metabolic Adaptations Leading to an Increased Intracellular Persistence. Clin Infect Dis. 2019;69 (11):1937-1945. doi: <a href='http:\/\/dx.doi.org\/10.1093\/cid\/ciz106'>10.1093\/cid\/ciz106<\/a>. PubMed <a href='http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/30753350'>PMID:30753350<\/a> .<\/li><li>L\u00e9cuyer, H, Nassif, X, Coureuil, M. [Meningococcus purpura fulminans, a partially solved mystery]. Med Sci (Paris). 2018;34 (12):1038-1041. doi: <a href='http:\/\/dx.doi.org\/10.1051\/medsci\/2018288'>10.1051\/medsci\/2018288<\/a>. PubMed <a href='http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/30623761'>PMID:30623761<\/a> .<\/li><li>Le Gallou, S, Zhou, Z, Thai, LH, Fritzen, R, de Los Aires, AV, M\u00e9gret, J <i>et al.<\/i>. A splenic IgM memory subset with antibacterial specificities is sustained from persistent mucosal responses. J Exp Med. 2018;215 (8):2035-2053. doi: <a href='http:\/\/dx.doi.org\/10.1084\/jem.20180977'>10.1084\/jem.20180977<\/a>. PubMed <a href='http:\/\/www.ncbi.nlm.nih.gov\/pubmed\/29959173'>PMID:29959173<\/a> PubMed Central <a href='http:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6080908'>PMC6080908<\/a>.<\/ol><a href='http:\/\/www.ncbi.nlm.nih.gov\/pubmed?term=(nassif,+xavier[Author])+AND+Inserm[Affiliation]'>Search PubMed<\/a>\n","protected":false},"excerpt":{"rendered":"<p>Xavier Nassif, M.D-PhD, is Professor of Microbiology at the Medical School Paris Descartes. He earned his Medical Degree in 1987 and completed his PhD at Institut Pasteur in 1989. 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