Trends Microbiology – Microbe of the Month – Neisseria meningitidis
01/01/2025. Neisseria meningitidis. Emmanuelle Bille, Alexandra Schubert-Unkmeir and Mathieu Coureuil, Trends Microbiology 2025
New commers in the Lab
01/10/2024. We are delighted to welcome three new members: Lison Reboul for a thesis with Emmanuelle Bille on phage biologyRomina Mehrabdollahi for a Master 2 internship with Mathieu Coureuil on …
Expanding the genetic toolbox for Neisseria meningitidis
14/08/2024. Expanding the genetic toolbox for Neisseria meningitidis with efficient tools for unmarked gene editing, complementation, and labelingMorgane Wuckelt et al Applied and Environmental Microbiology 2024 ABSTRACT The efficient natural transformation of Neisseria …
Grant ANR PRC
24/07/2024. Mathieu Coureuil was granted ANR PRC for two project Deciphering the role of Endothelial MicroParticles in CARdiovascular Dysfunctions in bacterial sepsis (EMPCard) — Unravelling the molecular mechanisms of action …
Grant ANR PRC and PRME
24/07/2023. Emmanuelle Bille was granted ANR PRME for her project on N. meningitidis and filamentous phage biology. The Neisseria group was also granted ANR PRC in collaboration with Sandrine Bourdoulous. …
Congratulation to Morgane Wuckelt and Elif UYAR
24/07/2023 .Morgane Wuckelt and Elif Uyar have been awarded a PhD Track Grant from BioSPC. We are all very proud and very excited about the science to come. Morgane will …
Engineered human microvasculature to study human infectious diseases
27/03/2023 . Implantation of engineered human microvasculature to study human infectious diseases in mouse models.Sophia Schönherr-Hellec et al iScience 2023 Animal models for studying human pathogens are crucially lacking. We …
Mechanical Activation of the β2-Adrenergic Receptor by Meningococci (Review)
02/05/2022 .Mechanical Activation of the β2-Adrenergic Receptor by Meningococcus: A Historical and Future Perspective Analysis of How a Bacterial Probe Can Reveal Signalling Pathways in Endothelial Cells, and a Unique …
The minor pilin PilV is necessary for meningococcal type IV pilus adhesion
12/11/2021 .The minor pilin PilV provides a conserved adhesion site throughout the antigenically variable meningococcal type IV pilus Jean-Philippe Barnier et al PNAS 2021 Neisseria meningitidis utilizes type IV pili (T4P) …
Congratulation to Audrey LAURENT, Clémence MOUVILLE and Xiali FU
02/08/2021 .Audrey LAURENT and Clémence MOUVILLE have been awarded a PhD Track Grant from BioSPC. Xiali FU has been awarded a PhD Track Grant from China Scholarship Council. We are …
Type IV pilus retraction enables sustained bacteremia
Le 19/02/2021 .Type IV pilus retraction enables sustained bacteremia and plays a key role in the outcome of meningococcal sepsis in a humanized mouse model. Jean-Philippe Barnier et al PLOS …
Type IV Pili recognize a Complex N-glycan
Receptor Recognition by Meningococcal Type IV Pili Relies on a Specific Complex N-glycan. Leguennec et al Proc Natl Acad Sci U S A, 117 (5), 2606-2612 2020 Feb 4 News linked to Mathieu …
Sialic Acid Mediates β2AR activation by type IV pili
Sialic Acid Mediated Mechanical Activation of β 2 Adrenergic Receptors by Bacterial Pili. Virion et al, Nat Commun, 10 (1), 4752 2019 Oct 18 News linked to Mathieu Coureuil & Xavier Nassif …